Yeah I’ve read the article and I’ve gone and had a little look at the scientific paper as well. The paper only mentions the effect of the molecule on cancer cells and does not mention what effect it has or may have on normal tissue. Interestingly for their mice model they delivered the drug intratumourally. To me this suggests that the drug is not selectively taken up by the tumour cells and they you need to get around this by limiting the delivery of the drug to the site of the cancer. This is just my speculation though. However, if true it would have implications on the practicality of using this method as a cancer therapy.
For some cancers at least injecting intratumourally is feasible, especially so in early stages. If that could be achieved on a large scale in clinical trials, or hell even in bovine or porcine studies (no idea what they use for cancer typically, I’d assume porcine due to genetic similarity?), it would be a great step forward.
Yeah I’ve read the article and I’ve gone and had a little look at the scientific paper as well. The paper only mentions the effect of the molecule on cancer cells and does not mention what effect it has or may have on normal tissue. Interestingly for their mice model they delivered the drug intratumourally. To me this suggests that the drug is not selectively taken up by the tumour cells and they you need to get around this by limiting the delivery of the drug to the site of the cancer. This is just my speculation though. However, if true it would have implications on the practicality of using this method as a cancer therapy.
For some cancers at least injecting intratumourally is feasible, especially so in early stages. If that could be achieved on a large scale in clinical trials, or hell even in bovine or porcine studies (no idea what they use for cancer typically, I’d assume porcine due to genetic similarity?), it would be a great step forward.