Okay, then it simply has an issue with the addresses you are providing, as someone pointed out already, the issue likely is the 192.168.100 network. Find out where exactly you define localhost and 192.168.100.1 as addresses to listen to and change them to e.g. 0.0.0.0 and 127.0.0.1 instead (or ideally just 0.0.0.0 as this includes localhost as well). Restart the container afterwards, see if it works. Of course make a backup of your config first so you can go back.
Geekworm offers a HAT and an enclosure for 2HDD and the Pi, that might suit you